BDBM50393720 CHEMBL2159122::CHEMBL3216329

SMILES COc1ccc(CN(C(C)c2nc(c[nH]2)-c2ccccc2)C(=O)C(N)Cc2c(C)cc(cc2C)C(N)=O)cc1C(O)=O

InChI Key InChIKey=QFNHIDANIVGXPE-UHFFFAOYSA-N

Data  4 KI  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50393720   

TargetDelta-type opioid receptor(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]-astemizole from human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataEC50:  1nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataEC50:  1.60E+3nMAssay Description:Agonist activity at kappa opioid receptor guinea pig colon tissueMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at delta opioid receptor expressed in CHO-hg cells by [35S]-GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataKi:  0.900nMAssay Description:Binding affinity to rat mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to rat delta opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataKi:  1.70nMAssay Description:Binding affinity to human mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50393720(CHEMBL2159122 | CHEMBL3216329)
Affinity DataKi:  55nMAssay Description:Binding affinity to guinea pig kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed