BDBM50393641 CHEMBL2158686

SMILES CCCCCCCCc1ccc(CC[C@@](N)(CO)COC)cc1

InChI Key InChIKey=YEYZALQTJCVXIJ-UHFFFAOYSA-N

Data  5 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50393641   

TargetSphingosine kinase 1(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of human SphK1 using sphingosine as substrate after 15 to 20 mins in presence of [gamma-32P]ATP by Cerenkov counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human SphK2 using sphingosine as substrate after 15 to 20 mins in presence of [gamma-32P]ATP by Cerenkov counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2019
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataKi:  1.65E+4nMAssay Description:Inhibition of SphK2 using sphingosine as substrate and [32gammaP]ATP after 15 to 20 mins by Cerenkov counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataKi:  1.65E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/15/2017
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataKi:  1.65E+4nMAssay Description:Inhibition of SK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataKi:  1.65E+4nMAssay Description:Inhibition of recombinant SphK2 (unknown origin) using sphingosine as substrate incubated for 15 to 20 mins by [gamma32P]-ATP based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2022
Entry Details Article
PubMed
TargetSphingosine kinase 2(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50393641(CHEMBL2158686)
Affinity DataKi:  2.70E+4nMAssay Description:Inhibition of SphK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2015
Entry Details Article
PubMed