BDBM50393572 CHEMBL2158488

SMILES CC(C)C(=O)Nc1ccc(cc1)C(=O)NC2(C(C(C2c3ccc(c(c3)OC)OC(=O)c4cccs4)(C(=O)O)NC(=O)c5ccc(cc5)NC(=O)C(C)C)c6ccc(c(c6)OC)OC(=O)c7cccs7)C(=O)O

InChI Key InChIKey=YCBYMFFEJARIGU-UHFFFAOYSA-N

Data  1 IC50  2 EC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393572   

TargetGlucagon-like peptide 1 receptor(Rat)
The National Center For Drug Screening

Curated by ChEMBL
LigandPNGBDBM50393572(CHEMBL2158488)
Affinity DataEC50:  203nMAssay Description:Agonist activity at rat GLP1R expressed in HEK293 cells assessed as stimulation of cAMP levels incubated for 6 hrs by multiple response element/cAMP ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlucagon-like peptide 1 receptor(Rat)
The National Center For Drug Screening

Curated by ChEMBL
LigandPNGBDBM50393572(CHEMBL2158488)
Affinity DataIC50: 300nMAssay Description:Inhibition of [125I]GLP1 (7-36) amide binding to rat GLP1R expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlucagon-like peptide 1 receptor(Human)
Nagasaki International University

Curated by ChEMBL
LigandPNGBDBM50393572(CHEMBL2158488)
Affinity DataEC50:  203nMAssay Description:Agonist activity at human GLP1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/23/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)