BDBM50393031 CHEMBL2152696

SMILES Cc1onc(-c2c(Cl)cccc2Cl)c1COc1ccc(-c2cccc(C(=O)O)c2)cc1

InChI Key InChIKey=LNTTUVPYVFRFTF-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50393031   

TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ERG by cell-based patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetBile acid receptor(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataEC50:  3.20E+3nMAssay Description:Inhibition of BACE1 expressed in HEK cells by cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetBile acid receptor(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataEC50:  3.20E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/5/2026
Entry Details PubMed
TargetBile acid receptor(Human)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataEC50:  3.60E+3nMAssay Description:Displacement of [3H]diprenorphine from human cloned delta receptor by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed
TargetLeukemia inhibitory factor receptor(Homo sapiens)
University of Naples "Federico II"

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50393031BDBM50393031(CHEMBL6096604)
Affinity DataIC50: 6.65E+3nMAssay Description:Concentration required to inhibit the VCAM-Very late antigen4 (VLA4) interaction in Ramos cell-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/2/2026
Entry Details PubMed