BDBM50392938 CHEMBL2152237

SMILES C[C@@]1(CCCN1S(=O)(=O)c1cccc2cccnc12)C(=O)N[C@H]1C2CC3CC1C[C@](O)(C3)C2

InChI Key

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392938   

LigandPNGBDBM50392938(CHEMBL2152237)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human 11betaHSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392938(CHEMBL2152237)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse 11betaHSD1 by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392938(CHEMBL2152237)
Affinity DataIC50: 11nMAssay Description:Inhibition of mouse 11betaHSD1 in 3T3L1 cells assessed as conversion of [1,2-(N)3H]-cortisone to cortisol after 1 hr by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50392938(CHEMBL2152237)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11betaHSD2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed