BDBM50392792 CHEMBL2151322::US8486966, 7

SMILES CC(C)Oc1cc(n[nH]1)-n1cnc2ccc(N[C@@H](CO)c3ccc(F)cn3)nc12

InChI Key InChIKey=CEDQYWYBSMPQAF-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392792   

TargetHigh affinity nerve growth factor receptor(Human)
Astrazeneca

US Patent

LigandBDBM50392792(CHEMBL2151322 | US8486966, 7)Copy SMILESCopy InChI

Affinity DataIC50: 3nMT: 2°CAssay Description:To measure JAK2 kinase activity, a commercially available purified enzyme may be used. The enzyme may be a C-terminal His6-tagged, recombinant, human...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
8/12/2013
Entry Details
Copy Entry DOIGo to US Patent

Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50392792(CHEMBL2151322 | US8486966, 7)Copy SMILESCopy InChI

Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL