BDBM50392646 CHEMBL2153558

SMILES COc1cccc(OC)c1OCCNC[C@@H]1COc2cccc(F)c2O1

InChI Key InChIKey=UUHRDARWBGSDJU-UHFFFAOYSA-N

Data  4 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392646   

TargetAlpha-1D adrenergic receptor(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50392646(CHEMBL2153558)
Affinity DataKi:  7.41nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1D adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-1A adrenergic receptor(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50392646(CHEMBL2153558)
Affinity DataKi:  18.2nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1A adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Rat)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50392646(CHEMBL2153558)
Affinity DataKi:  31.6nMAssay Description:Displacement of [3H]-8-OH-DPAT from 5-HT1A receptor in rat hippocampal membranes after 30 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetAlpha-1B adrenergic receptor(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50392646(CHEMBL2153558)
Affinity DataKi:  102nMAssay Description:Displacement of [3H]prazosin from human cloned alpha1B adrenoceptor expressed in CHO cell membranes after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed