BDBM503925 US11034692, Compound 205::trans-N-(8-amino-5-methyl-6-(4- methylpyridin-3-yl)-2,7-naphthyridin-3- yl)-2- (cyanomethyl)cyclopropanecarboxamide

SMILES Cc1ccncc1-c1nc(N)c2cnc(NC(=O)[C@H]3C[C@@H]3CC#N)cc2c1C

InChI Key InChIKey=VOYOLLACSNQFJX-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503925   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM503925(trans-N-(8-amino-5-methyl-6-(4- methylpyridin-3-yl...)Copy SMILESCopy InChI

Affinity DataKi:  0.0880nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/5/2021
Entry Details
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