BDBM50392368 CHEMBL2151497

SMILES FC1(F)CCC(CC1)C(=O)N1CC(C1)c1nc(no1)-c1cccc(Cl)c1

InChI Key InChIKey=GBGNPCMUCLQITD-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392368   

TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392368(CHEMBL2151497)
Affinity DataEC50:  180nMAssay Description:Positive allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392368(CHEMBL2151497)
Affinity DataIC50: 1.00E+4nMAssay Description:Negative allosteric modulation of human mGluR5 expressed in recombinant HEK293 cells by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392368(CHEMBL2151497)
Affinity DataIC50: 2.50E+7nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Lundbeck Research Usa

Curated by ChEMBL
LigandPNGBDBM50392368(CHEMBL2151497)
Affinity DataIC50: 3.30E+7nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed