BDBM50392279 CHEMBL2153647

SMILES [#8]-[#6](=O)-[#6@H](-[#6]-[#6]-[#6](=O)-[#7]-1-[#6]-[#6]-[#7](-[#6]-[#6]-1)-c1cccc(c1)\[#7]=[#6]-1/[#7]-[#6]-[#6]-[#6]-[#7]-1)-[#7]-[#6](=O)-[#8]-[#6]-c1ccc(cc1)-[#6](-[#8])=O

InChI Key InChIKey=TZTYGQORWRHJNU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392279   

TargetIntegrin alpha-V/beta-3(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392279(CHEMBL2153647)
Affinity DataIC50: 0.0820nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta3 after 3 hrs by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392279(CHEMBL2153647)
Affinity DataIC50: 2.20nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta5 after 3 hrs by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392279(CHEMBL2153647)
Affinity DataIC50: 17nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin over expressed in A2780 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392279(CHEMBL2153647)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin expressed in PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed