BDBM50392275 CHEMBL2153643

SMILES [#6]-[#6]-c1c2-[#6]-n3c(cc4c(-[#6]-[#8]-[#6](=O)[C@]4([#8])[#6]-[#6])c3=O)-c2nc2ccc(-[#8]-[#6](=O)-[#7]-3-[#6]-[#6]-[#7](-[#6]-[#6]-3)-[#6](=O)-c3ccc(-[#6]-[#8]-[#6](=O)-[#7]-[#6@@H](-[#6]-[#6]-[#6](=O)-[#7]-4-[#6]-[#6]-[#7](-[#6]-[#6]-4)-c4cccc(c4)\[#7]=[#6]-4/[#7]-[#6]-[#6]-[#6]-[#7]-4)-[#6](-[#8])=O)cc3)cc12

InChI Key InChIKey=WUEJDPFGPRMOTL-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50392275   

TargetIntegrin alpha-V/beta-3(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392275(CHEMBL2153643)
Affinity DataIC50: 1.30nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta3 after 3 hrs by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-5(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392275(CHEMBL2153643)
Affinity DataIC50: 1nMAssay Description:Displacement of [125I]echistatin from integrin alpha5beta5 after 3 hrs by gamma counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392275(CHEMBL2153643)
Affinity DataIC50: 89nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin over expressed in A2780 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetIntegrin alpha-V/beta-3(Human)
Sigma-Tau Industrie Farmaceutiche Riunite

Curated by ChEMBL
LigandPNGBDBM50392275(CHEMBL2153643)
Affinity DataIC50: 37nMAssay Description:Inhibition of vitronectin binding to human alphaVbeta3 integrin expressed in PC3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed