BDBM50392214 CHEMBL2153167

SMILES CC(C)CS(=O)(=O)CC(NC(=O)c1ccc(s1)-c1nnn[nH]1)C(=O)NCC#N

InChI Key InChIKey=BBRREBFQRGNSAL-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50392214   

TargetCathepsin S(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392214(CHEMBL2153167)
Affinity DataKi:  76nMAssay Description:Inhibition of human cathepsin S using Z-Phe-Val-Arg-pNA as substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin K(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392214(CHEMBL2153167)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of human cathepsin K using Z-Leu-Arg-AMC as substrate after 10 mins by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin F(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392214(CHEMBL2153167)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of human recombinant cathepsin F using Z-Phe-Arg-AMC as substrate after 8 min by fluorimetric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProcathepsin L(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392214(CHEMBL2153167)
Affinity DataKi: >4.00E+3nMAssay Description:Inhibition of human cathepsin L using Z-Phe-Arg-pNA as substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin B(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50392214(CHEMBL2153167)
Affinity DataKi:  3.40E+4nMAssay Description:Inhibition of human cathepsin B using Z-Arg-Arg-pNA as substrate after 10 mins by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed