BDBM50392175 CHEMBL2152944

SMILES OC[C@@H](O)COc1ccc2CCc3cc(Nc4ccc(F)cc4F)ccc3C(=O)c2c1

InChI Key InChIKey=HXMGCTFLLWPVFM-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50392175   

TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50392175(CHEMBL2152944)
Affinity DataIC50: 40nMAssay Description:Inhibition of p38alpha MAP kinase in whole blood (unknown origin) assessed as lipopolysaccharide-stimulated TNF-alpha release by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50392175(CHEMBL2152944)
Affinity DataIC50: 5nMAssay Description:Inhibition of p38alpha MAP kinase (unknown origin) by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50392175(CHEMBL2152944)
Affinity DataIC50: 40nMAssay Description:Inhibition of p38alpha-dependent TNFalpha production in human whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50392175(CHEMBL2152944)
Affinity DataIC50: 5nMAssay Description:Inhibition of p38alpha by immunosorbent based kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
University of T£Bingen

Curated by ChEMBL
LigandPNGBDBM50392175(CHEMBL2152944)
Affinity DataIC50: 5nMAssay Description:Inhibition of human p38 MAPK alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed