BDBM50392068 CHEMBL2152572

SMILES c1ccc(c(c1)C(=O)N)Nc2ccc(cc2)Cl

InChI Key InChIKey=NHAYLAZTTIMSEA-UHFFFAOYSA-N

Data  2 IC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392068   

TargetNAD-dependent protein deacetylase sirtuin-2(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50392068(CHEMBL2152572)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human recombinant SIRT2 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
Kyoto Prefectural University of Medicine

Curated by ChEMBL
LigandPNGBDBM50392068(CHEMBL2152572)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human recombinant SIRT1 using Fluor de Lys-SIRT as substrate incubated for 60 mins prior to substrate addition measured after 60 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed