BDBM50392015 CHEMBL2152406

SMILES CN1CCCC[C@H]1C(=O)N1CCC(CC1)n1cnc2cnc3[nH]ccc3c12

InChI Key InChIKey=RFPXHAIJTDKSBT-UHFFFAOYSA-N

Data  1 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50392015   

TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392015(CHEMBL2152406)
Affinity DataEC50:  1.80E+3nMAssay Description:Inhibition of JAK1 in human TF1 cells assessed as inhibition of IL2-induced STAT3 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
Argenta Discovery

Curated by ChEMBL
LigandPNGBDBM50392015(CHEMBL2152406)
Affinity DataKi:  11nMAssay Description:Inhibition of JAK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed