BDBM50391954 CHEMBL2152262

SMILES COc1ccc(cc1OC)-c1c[nH]c2ncc(cc12)-c1cccc(N)c1

InChI Key InChIKey=JPTMGCYMHIJHRQ-UHFFFAOYSA-N

Data  3 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50391954   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391954(CHEMBL2152262)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391954(CHEMBL2152262)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of c-KIT D816V mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetMast/stem cell growth factor receptor Kit(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391954(CHEMBL2152262)
Affinity DataIC50: 1.06E+3nMAssay Description:Inhibition of wild type c-KIT (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2016
Entry Details Article
PubMed
TargetHigh affinity nerve growth factor receptor(Human)
Korea Advanced Institute of Science and Technology (Kaist)

Curated by ChEMBL
LigandPNGBDBM50391954(CHEMBL2152262)
Affinity DataKd:  125nMAssay Description:Binding affinity to TRKA by high throughput assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed