BDBM50391948 CHEMBL2147767

SMILES COc1ccc2C(=O)C(Oc2c1CN1CCNCC1)=Cc1c[nH]c2ncccc12

InChI Key InChIKey=GZGLZFSLPIMAQV-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50391948   

TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391948(CHEMBL2147767)
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391948(CHEMBL2147767)
Affinity DataIC50: 390nMAssay Description:Inhibition of full length recombinant human N-terminal GST-tagged PIM2 (1 to 311 residues) expressed in baculovirus infected sf21 cells using S6K2 pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391948(CHEMBL2147767)
Affinity DataIC50: 0.840nMAssay Description:Inhibition of PIM1 (unknown origin) using 5-FAM-RSRHSSYPAGT-CONH2 as substrate after 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2019
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-3(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391948(CHEMBL2147767)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PIM3 (unknown origin) using FL-Peptide 1 (5-FAM-AKRRRLSSLRA-COOH) substrate incubated for 2 hrs by electrophoretic mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50391948(CHEMBL2147767)
Affinity DataIC50: 2nMAssay Description:Inhibition of PIM1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/18/2021
Entry Details Article
PubMed