BDBM50391890 CHEMBL2147420

SMILES C\C=C\c1ccc2oc(cc2c1)-c1ccc(O)cc1O

InChI Key InChIKey=SDWZWUUOXFFJSA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50391890   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of 5-lipoxygenase in human neutrophils assessed as inhibition of LTB4 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta treated human A549 cell microsomal membrane assessed as inhibition of PGE2 formation incubated for 15 mins before ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50391890(CHEMBL2147420)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of ram seminal vesicle COX1 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed