BDBM50391813 CHEMBL2146886

SMILES Fc1ccc(C(=O)N2CCC2)c(Nc2ccc(I)cc2F)c1F

InChI Key InChIKey=YVSXASJEPXDDQH-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50391813   

TargetDual specificity mitogen-activated protein kinase kinase 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50391813(CHEMBL2146886)Copy SMILESCopy InChI

Affinity DataIC50: 535nMAssay Description:Inhibition of MEK1-mediated ERK2 T202/Y204 phosphorylation using biotinylated MBP as substrate preincubated for 30 mins measured after 100 mins by cR...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL