BDBM50391779 CHEMBL2146880

SMILES CSc1cc(CCN2CCN(CCc3ccc4C(=O)OCc4c3)CC2)ccc1C#N

InChI Key InChIKey=HXVNLBDKDPCJNH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50391779   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50391779(CHEMBL2146880)Copy SMILESCopy InChI

Affinity DataIC50: 460nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50391779(CHEMBL2146880)Copy SMILESCopy InChI

Affinity DataIC50: 550nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL