BDBM50391769 CHEMBL2146872

SMILES O=C1OCc2cc(CCN3CCN(CCc4ccc5nonc5c4)CC3)ccc12

InChI Key InChIKey=IGWJOSUHQHWZMO-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391769   

TargetPotassium voltage-gated channel subfamily H member 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50391769(CHEMBL2146872)Copy SMILESCopy InChI

Affinity DataIC50: 280nMAssay Description:Displacement of [35S]MK499 from human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
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TargetATP-sensitive inward rectifier potassium channel 1(Human)
TBA

Curated by ChEMBL

LigandBDBM50391769(CHEMBL2146872)Copy SMILESCopy InChI

Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human ROMK1 channel expressed in CHO cells coexpressing DHFR assessed as inhibition of 86Rb+ efflux after 35 mins by TopCount methodMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
TBA

Curated by ChEMBL

LigandBDBM50391769(CHEMBL2146872)Copy SMILESCopy InChI

Affinity DataIC50: 280nMAssay Description:Inhibition of hERG (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/20/2024
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL