BDBM50391678 CHEMBL1569494

SMILES [#6]-[#8]-[#6](=O)-[#6](=[#6]/c1ccccc1-[#7+](-[#8-])=O)\[#6](=O)-[#8]-[#6]

InChI Key InChIKey=BYLJWBQJQJHQDR-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391678   

TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50391678(CHEMBL1569494)
Affinity DataIC50: 310nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of NO production after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50391678(CHEMBL1569494)
Affinity DataIC50: 420nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of IL1-beta production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetToll-like receptor 4(Mouse)
University of Colorado At Boulder

Curated by ChEMBL
LigandPNGBDBM50391678(CHEMBL1569494)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of TLR4 in LPS-stimulated mouse RAW264.7 cells assessed as reduction of TNFalpha production after 24 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed