BDBM50391300 CHEMBL162691

SMILES OC(=O)CC\C=C/CO[C@H]1[C@@H](CC[C@@H]1N1CCCCCC1)OCc1ccc(cc1)-c1ccncc1

InChI Key InChIKey=HCLFUHWPLXVRIS-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391300   

TargetThromboxane-A synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50391300(CHEMBL162691)
Affinity DataIC50: 631nMAssay Description:In vitro TXA2 synthase antagonism through inhibition of collagen induced thromboxane-A2 production in human citreated whole bloodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetThromboxane A2 receptor(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50391300(CHEMBL162691)
Affinity DataKd:  79.4nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced contraction of rat isolated thoracic aortic stripMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article

TargetThromboxane A2 receptor(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50391300(CHEMBL162691)
Affinity DataKd:  10nMAssay Description:In vitro thromboxane A2 receptor antagonism through inhibition of U-46619-induced platelet aggregation in human whole blood.More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article