BDBM50391281 CHEMBL5286642

SMILES OC(=O)C(O)=O.CC(C)n1nc(-c2nnc(o2)C2CCN(CCc3ccccc3)CC2)c2ccccc12

InChI Key InChIKey=STENMHAOBIBZMX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391281   

Target5-hydroxytryptamine receptor 4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50391281(CHEMBL5286642)
Affinity DataEC50:  24nMAssay Description:Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50391281(CHEMBL5286642)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 2 mins in presence of NADPH regenerating system by LC-MS/MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50391281(CHEMBL5286642)
Affinity DataIC50: 1.39E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed