BDBM50391267 CHEMBL5289747

SMILES OC(=O)C(O)=O.CC(C)n1nc(C(=O)NC2C3CN(CC4CCOCC4)CC23)c2ccccc12

InChI Key InChIKey=OLXNWUWZVKDKSX-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50391267   

Target5-hydroxytryptamine receptor 4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50391267(CHEMBL5289747)
Affinity DataEC50:  12nMAssay Description:Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50391267(CHEMBL5289747)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 2 mins in presence of NADPH regenerating system by LC-MS/MS...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50391267(CHEMBL5289747)
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed