BDBM50391246 CHEMBL5275895
SMILES OC(C(O)C(O)=O)C(O)=O.CC(C)n1nc(C(=O)NC2CCN(CC(C)(C)O)CC2)c2ccccc12
InChI Key InChIKey=OLBZGSQZXOFDNN-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50391246
Affinity DataEC50: 29nMAssay Description:Partial agonist activity at human 5HT4E receptor expressed in CHO cells assessed as cAMP accumulation incubated for 4 hrs by luciferase reporter gene...More data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Suven Life Sciences
Curated by ChEMBL
Suven Life Sciences
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of hERG expressed in HEK293 cells at holding potential of -80 mV by whole cell patch clamp assayMore data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate incubated for 2 mins in presence of NADPH regenerating system by LC-MS/MS...More data for this Ligand-Target Pair
Affinity DataIC50: 4.50E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate incubated for 12 mins in presence of NADPH regenerating system by ...More data for this Ligand-Target Pair