BDBM50391226 CHEMBL265493

SMILES Nc1ncc(Cc2ccccc2)c(N)n1

InChI Key InChIKey=XHPZVBGIPQQTQW-UHFFFAOYSA-N

Data  16 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 18 hits for monomerid = 50391226   

TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataIC50: 1.95E+3nMAssay Description:Compound was tested for inhibition of Escherichia coli Dihydrofolate reductase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataIC50: 3.39E+3nMAssay Description:Inhibition of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  660nMAssay Description:Inhibition constant against binding of Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2019
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  661nMAssay Description:Apparent inhibitory (log 1/Ki) activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/31/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  661nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Escherichia coli (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Salmonella typhi)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  661nMAssay Description:Inhibitory activity against Escherichia coli dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Escherichia coli)
University of Illinois At Chicago 60612

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  661nMAssay Description:Compound is evaluated for the inhibition of dihydrofolate reductase from Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  2.14E+3nMpH: 7.2Assay Description:Inhibitory activity against bovine liver dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Bovine)
TBA

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of dihydrofolate reductase from bovine liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of California

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibition of Dihydrofolate reductase from Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of California

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibitory activity against dihydrofolate reductase (DHFR) from Lactobacillus casei (expressed as log 1/Kiapp)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/6/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
University of California

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  6.31E+3nMAssay Description:Inhibitory activity against Lactobacillus casei dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  1.95E+4nMAssay Description:Compound was evaluated for inhibitory activity against chicken dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  1.95E+4nMAssay Description:Inhibition of chicken liver Dihydrofolate reductase (dihydrofolate reductase)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2020
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  1.95E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  1.95E+4nMpH: 7.2Assay Description:Inhibitory activity against chicken dihydrofolate reductase at pH 7.2.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2018
Entry Details Article
PubMed
TargetDihydrofolate reductase(Chicken)
Pomona College

Curated by ChEMBL
LigandPNGBDBM50391226(CHEMBL265493)
Affinity DataKi:  1.95E+4nMAssay Description:Inhibitory activity against chicken liver dihydrofolate reductaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/19/2013
Entry Details Article
PubMed