BDBM50391076 CHEMBL2087344

SMILES O=C(N[C@@H]1CO[C@@H]2[C@@H](CO[C@H]12)OCc1ccccc1)C(\NC(=O)c1ccccc1)=C\c1ccc2OCOc2c1

InChI Key InChIKey=MNCOOLKRGJFUMT-UHFFFAOYSA-N

Data  2 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50391076   

TargetKallikrein-7(Human)
Universidade Federal Do Tri£Ngulo Mineiro

Curated by ChEMBL
LigandPNGBDBM50391076(CHEMBL2087344)
Affinity DataIC50: 2.05E+5nMAssay Description:Inhibition of human recombinant KLK7 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetKallikrein-5 [D153N](Human)
Universidade Federal Do Tri£Ngulo Mineiro

Curated by ChEMBL
LigandPNGBDBM50391076(CHEMBL2087344)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human recombinant KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by FRET analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetKallikrein-7(Human)
Universidade Federal Do Tri£Ngulo Mineiro

Curated by ChEMBL
LigandPNGBDBM50391076(CHEMBL2087344)
Affinity DataKi:  8.03E+4nMAssay Description:Competitive inhibition of recombinant human KLK7 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetKallikrein-5 [D153N](Human)
Universidade Federal Do Tri£Ngulo Mineiro

Curated by ChEMBL
LigandPNGBDBM50391076(CHEMBL2087344)
Affinity DataKi:  3.57E+5nMAssay Description:Competitive inhibition of human KLK5 expressed in insect cell/baculovirus using Abz-KLYSSKQ-EDDnp as substrate by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed