BDBM50390670 CHEMBL2070191

SMILES Clc1cccc(Nc2ncnc3ccc(NCc4ccc5OCOc5c4)cc23)c1

InChI Key InChIKey=CVXGWPCZIJNFAQ-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50390670   

TargetEpidermal growth factor receptor(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50390670(CHEMBL2070191)
Affinity DataIC50: 570nMAssay Description:Inhibition of EGFR in human A431 cell lysate using tyrosine/glutamic acid polymer as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetReceptor tyrosine-protein kinase erbB-2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50390670(CHEMBL2070191)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of recombinant HER2 expressed in baculovirus infected Sf9 cells using [32P]ATP incubated for 30 mins prior to ATP addition measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Nanjing University

Curated by ChEMBL
LigandPNGBDBM50390670(CHEMBL2070191)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of VEGFR2 using ATP incubated for 30 mins prior to ATP addition measured after 60 mins by fluorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed