BDBM50390629 CHEMBL2069600

SMILES COc1ccc(C2=NNC(=O)CC2C)c2cc(nn12)C(F)(F)F

InChI Key InChIKey=IDPCPRHAKGSESY-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50390629   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50390629(CHEMBL2069600)
Affinity DataIC50: 70nMAssay Description:Inhibition of PDE4B (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50390629(CHEMBL2069600)
Affinity DataIC50: 2.38E+3nMAssay Description:Inhibition of PDE3A (unknown origin) by radiochemical assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50390629(CHEMBL2069600)
Affinity DataIC50: 360nMAssay Description:Inhibition of core catalytic domain of PDE3AMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50390629(CHEMBL2069600)
Affinity DataIC50: 42nMAssay Description:Inhibition of core catalytic domain of PDE4BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50390629(CHEMBL2069600)
Affinity DataIC50: 360nMAssay Description:Inhibition of core catalytic domains PDE3A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Kyorin Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50390629(CHEMBL2069600)
Affinity DataIC50: 42nMAssay Description:Inhibition of core catalytic domains PDE4B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed