BDBM50390470 CHEMBL2071507

SMILES CC(C)C(NC(=O)c1cc(Cl)ccc1C(F)(F)F)C(=O)c1ccc(cc1)C#N

InChI Key InChIKey=GDCSGNPQQSANAH-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50390470   

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50390470(CHEMBL2071507)Copy SMILESCopy InChI

Affinity DataIC50: 398nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Ca2+-induced intracellular calcium flux by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/8/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetTransient receptor potential cation channel subfamily A member 1(Human)
Astrazeneca

Curated by ChEMBL

LigandBDBM50390470(CHEMBL2071507)Copy SMILESCopy InChI

Affinity DataIC50: 316nMAssay Description:Antagonist activity at human TRPA1 expressed in HEK293 cells assessed as inhibition of Zn2+-induced intracellular calcium flux by FLIPR assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/8/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL