BDBM50390334 CHEMBL2070735

SMILES Cc1nc(N)c2nnn(C[C@H]3CN(Cc4nccs4)CCO3)c2n1

InChI Key InChIKey=QGTJGTFOISKMAD-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50390334   

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8B(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50390334(CHEMBL2070735)Copy SMILESCopy InChI

Affinity DataIC50: 1.30nMAssay Description:Inhibition of PDE8B expressed in Sf9 insect cellsMore data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/8/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetHigh affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50390334(CHEMBL2070735)Copy SMILESCopy InChI

Affinity DataIC50: 1.90nMAssay Description:Inhibition of PDE8AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/8/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPotassium voltage-gated channel subfamily H member 2(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50390334(CHEMBL2070735)Copy SMILESCopy InChI

Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProtUniProtKB/TrEMBL
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
2/8/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL