BDBM50390259 CHEMBL2070412

SMILES CN1CCN(CCCOc2ccc(cc2)N2C(=S)S\C(=C/c3ccc(Oc4cccc(c4)C(N)=O)cc3)C2=O)CC1

InChI Key InChIKey=CDSCWARZCDEAKD-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50390259   

LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of IKKbeta in mouse CIA model splenocytes assessed as inhibition of TNFalpha production after 72 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of IKKalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MAPK p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 11(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of MAPK p38betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of IKKbeta using 5FAM-GRHDSGLDSMK-NH2 as substrate incubated for 10 mins prior to substrate addition by IMAP-TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Korea University

Curated by ChEMBL
LigandPNGBDBM50390259(CHEMBL2070412)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of JNK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed