BDBM50389931 CHEMBL2071066

SMILES CCc1c([nH]c2ccc(Cl)cc12)C(=O)NCCc1ccc(F)cc1

InChI Key InChIKey=LYYFSBQHOLAWII-UHFFFAOYSA-N

Data  1 IC50  5 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50389931   

TargetCannabinoid receptor 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50389931(CHEMBL2071066)
Affinity DataEC50:  8.96E+3nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 15 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50389931(CHEMBL2071066)
Affinity DataEC50:  7.37E+3nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 5 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50389931(CHEMBL2071066)
Affinity DataEC50:  4.58E+3nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation after 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50389931(CHEMBL2071066)
Affinity DataEC50:  4.99E+3nMAssay Description:Activity at hemagglutinin-tagged human CB1 receptor expressed in HEK293 cells assessed as effect on forskolin-induced cAMP accumulation in presence o...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2016
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50389931(CHEMBL2071066)
Affinity DataEC50: >1.00E+4nMAssay Description:Allosteric modulation of human recombinant CB1 receptor expressed in HEK293 cells assessed as stimulation of [3H]CP55940 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50389931(CHEMBL2071066)
Affinity DataIC50: 1.00E+4nMAssay Description:Allosteric modulation of human recombinant CB2 receptor expressed in HEK293 cells assessed as inhibition of [3H]CP55940 bindingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed