BDBM50389711 CHEMBL2070078::US10307425, Example 113::US10632122, Example 113

SMILES CCOc1ccc2cc(ccc2c1)-c1nn(C2CCN(CCCN)CC2)c2ncnc(N)c12

InChI Key InChIKey=UAAQWLWCHSPTEB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389711   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50389711(CHEMBL2070078 | US10307425, Example 113 | US106321...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphor imaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCAM kinase, CDPK family TgCDPK1(Toxoplasma gondii (strain ATCC 50861 / VEG))
University of Washington

US Patent
LigandPNGBDBM50389711(CHEMBL2070078 | US10307425, Example 113 | US106321...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details
Go to US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

US Patent
LigandPNGBDBM50389711(CHEMBL2070078 | US10307425, Example 113 | US106321...)
Affinity DataIC50: 4.30nMAssay Description:Inhibitors were evaluated in triplicate in eight-point dilutions (3-fold dilutions) during the enzymatic reactions. TgCDPK1 enzymatic inhibition was ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/10/2021
Entry Details
Go to US Patent