BDBM50389682 CHEMBL2070049::US10544104, Compound 137::US9518026, Example 4::US9765037, Compound 137::US9956214, Compound 4

SMILES CCOc1ccc2cc(ccc2c1)-c1nn(c2ncnc(N)c12)C(C)(C)C

InChI Key InChIKey=BJNUCAZGXXFVAJ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50389682   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human SRC using Ac-EIYGEFKKK-OH as substrate after 60 mins by phosphor imaging methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 33nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 43nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/14/2019
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

TargetTyrosine-protein kinase ABL1(Human)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of human tyrosine kinases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/29/2019
Entry Details
Go to US Patent

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 33nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent

TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 43nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2020
Entry Details
Go to US Patent

TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 2.21E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent

TargetTyrosine-protein kinase ABL1(Human)
University of Washington Through Its Center For Commercialization

US Patent
LigandPNGBDBM50389682(CHEMBL2070049 | US9518026, Example 4 | US9765037, ...)
Affinity DataIC50: 8.04E+3nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/1/2020
Entry Details
Go to US Patent