BDBM50389653 CHEMBL2069921

SMILES C(N1CCN(Cc2ccccc2)CC1)c1nc(no1)-c1ccccc1

InChI Key InChIKey=AGMZWJCXRAGFQR-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50389653   

TargetCytochrome P450 1A2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389653(CHEMBL2069921)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP1A2 coexpressed in Escherichia coli using phenacetin as probeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389653(CHEMBL2069921)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C19 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C8(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389653(CHEMBL2069921)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP2C8 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389653(CHEMBL2069921)
Affinity DataIC50: 1.02E+4nMAssay Description:Inhibition of human recombinant CYP2D6 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50389653(CHEMBL2069921)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of human ERG channel expressed in CHO cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50389653(CHEMBL2069921)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant CYP3A4 coexpressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed