BDBM50389590 CHEMBL2069502

SMILES C1CC(CCO1)[C@H]1N[C@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccccc1

InChI Key InChIKey=WTEHMPUGVAOZBF-UHFFFAOYSA-N

Data  1 KI  19 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 50389590   

TargetSomatostatin receptor type 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mouse SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human SST2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human SST1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 380nMAssay Description:Displacement of [35S]MK499 from human Erg expressed in HEK293 cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]SS-14 from human SST3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mouse SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 2(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mouse SST2 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 1(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity to mouse SST1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 5(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human SST5 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 4(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 1.00E+3nMAssay Description:Binding affinity to human SST4 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 11nMAssay Description:Inhibition of human SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 14nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 14nMAssay Description:Binding affinity to human somatostatin receptor type 3More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataEC50:  22nMAssay Description:Antagonist activity at human somatostatin receptor type 3 assessed as inhibition of cAMP levelsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 380nMAssay Description:Binding affinity to human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/7/2017
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 22nMAssay Description:Antagonist activity at human SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 8.90nMAssay Description:Displacement of [125I]SS-14 from mouse SST3 receptor expressed in CHO cells after 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 16nMAssay Description:Antagonist activity at mouse SST3 receptor expressed in CHO cells assessed as inhibition of forskolin/SS-14-stimulated cAMP accumulation preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataIC50: 16nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50389590(CHEMBL2069502)
Affinity DataKi:  369nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed