BDBM50389487 CHEMBL2063048

SMILES O=C1NCNC(NCc2ccco2)=N1

InChI Key InChIKey=BTIKIXQZBCJTQP-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50389487   

TargetDNA (cytosine-5)-methyltransferase 1(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50389487(CHEMBL2063048)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of DNMT1 in human HeLa cell nuclear extract assessed as methylated substrate level by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetOrphan methyltransferase M.SssI(Spiroplasma monobiae strain MQ-1)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50389487(CHEMBL2063048)
Affinity DataIC50: 2.73E+3nMAssay Description:Inhibition of Spiroplasma sp. MQ1 SssI methyltransferase-mediated DNA cytosine methylation using pUC18 as substrate and [3H]CH3-SAM measured up to 10...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetOrphan methyltransferase M.SssI(Spiroplasma monobiae strain MQ-1)
Polish Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50389487(CHEMBL2063048)
Affinity DataKi:  700nMAssay Description:Competitive inhibition of Spiroplasma sp. MQ1 SssI methyltransferase using pUC18 as substrate measured for 10 mins by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed