BDBM50389099 CHEMBL2064544

SMILES COc1ccc(cc1)S(=O)(=O)N(Cc1ccc(OCCOCCOCCOCCn2cc(COCCOCCOCCOCCOCCF)nn2)cc1)[C@H](C(C)C)C(=O)NO

InChI Key InChIKey=JZHHNBACJYFNCE-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50389099   

Target72 kDa type IV collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389099(CHEMBL2064544)
Affinity DataIC50: 4nMAssay Description:Inhibition of MMP2 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389099(CHEMBL2064544)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP8 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMatrix metalloproteinase-9(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389099(CHEMBL2064544)
Affinity DataIC50: 3nMAssay Description:Inhibition of MMP9 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incuba...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCollagenase 3(Human)
University Hospital M£Nster

Curated by ChEMBL
LigandPNGBDBM50389099(CHEMBL2064544)
Affinity DataIC50: 1nMAssay Description:Inhibition of MMP13 using (7-methoxycoumarin-4-yl)acetyl-Pro-Leu-Gly-Leu-(3-(2,4-dinitrophenyl)-L-2,3-diaminopropionyl)Ala-Arg-NH2 as substrate incub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed