BDBM50388776 CHEMBL2062581

SMILES CC(=O)Nc1ccc2[nH]cc(-c3cc(NC4CC4)n4ncc(C#N)c4n3)c2c1

InChI Key InChIKey=UZZGMJZTCZOSGC-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50388776   

TargetCasein kinase II subunit alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388776(CHEMBL2062581)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of full length N-terminus His-tagged human CK2alpha expressed in insect Sf21 cells using BODIPY-FL-RRRDDDSDDD-CONH2 as substrate after 20 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase II subunit alpha(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388776(CHEMBL2062581)
Affinity DataIC50: 77nMAssay Description:Inhibition of CK2alpha in human HCT116 cells assessed as decrease in AKT phosphorylation at S129 residue after 3 to 24 hrs by Western blot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388776(CHEMBL2062581)
Affinity DataIC50: 250nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50388776(CHEMBL2062581)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed