BDBM50388737 CHEMBL2058860

SMILES CCCc1nc2c(C)cc(cc2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1)C(=O)NCC(C)c1ccccc1

InChI Key InChIKey=SESMVBDEQODYAX-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388737   

TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataIC50: 0.900nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from angiotensin AT1 receptor after 180 mins by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Rabbit)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataKd:  1.70nMAssay Description:Antagonist activity at AT1 receptor in Japanese white rabbit thoracic aorta assessed as inhibition of KCl-induced contraction incubated 30 mins post ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetType-1 angiotensin II receptor(Human)
School of Chemical Engineering & The Environment

Curated by ChEMBL
LigandPNGBDBM50388737(CHEMBL2058860)
Affinity DataIC50: 17nMAssay Description:Displacement of [125I]Sar1Ile8-Ang2 from human AT1 receptor expressed in CHO-K1 cell membranes after 180 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMed