BDBM50388712 CHEMBL2059870

SMILES Cc1nn(C)c(C)c1-c1ccc(C)c(NC(=O)c2ccc(OCc3ccccn3)cc2)c1

InChI Key InChIKey=SBHODUNGGJKTHR-UHFFFAOYSA-N

Data  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388712   

TargetSmoothened homolog(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388712(CHEMBL2059870)
Affinity DataIC50: 12nMAssay Description:Inhibition of Smo expressed in mouse NIH/3T3 cells after 20 hrs by Gli reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetSmoothened homolog(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388712(CHEMBL2059870)
Affinity DataEC50:  8nMAssay Description:Inhibition of Smo expressed in mouse C3H10T1/2 cells assessed as reduction in alkaline phosphatase level after 72 hrs by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50388712(CHEMBL2059870)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed