BDBM50388667 CHEMBL2059323

SMILES Fc1ccc2n(C3CCN(CCCN4C(=O)COc5ccccc45)CC3)c(=O)[nH]c2c1

InChI Key InChIKey=YKMMIZDDGKTHST-UHFFFAOYSA-N

Data  1 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50388667   

TargetMuscarinic acetylcholine receptor M1(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50388667(CHEMBL2059323)
Affinity DataEC50:  66nMAssay Description:Agonist activity at human M1 receptor expressed in CHO-K1 cells assessed as calcium mobilization for 6 mins by Calcium4-based stainingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50388667(CHEMBL2059323)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human ERG expressed in CHO cells after 30 mins by Rb+ flux assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
H. Lundbeck

Curated by ChEMBL
LigandPNGBDBM50388667(CHEMBL2059323)
Affinity DataKi:  2.5nMAssay Description:Displacement of [3H]raclopride from human D2L receptor expressed in CHO cells after 60 mins by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed