BDBM50388546 CHEMBL213072::CHEMBL333363

SMILES NCCCn1c2-c3ccccc3C(=O)c2c2ccccc2c1=O

InChI Key InChIKey=JWMIPWLLAVVHDH-UHFFFAOYSA-N

Data  1 KI  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50388546   

TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL333363 | CHEMBL213072)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of recombinant Tdp1 (unknown origin) using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL333363 | CHEMBL213072)
Affinity DataEC50:  8.66E+3nMAssay Description:Activation of human RXRalpha activity expressed in COS1 cells after 12 hrs by RXRE-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL333363 | CHEMBL213072)
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of human recombinant Tdp1 using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-phosphotyrosine as substrate assessed a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL333363 | CHEMBL213072)
Affinity DataIC50: 2.95E+4nMAssay Description:Inhibition of human Tdp1 in Tdp1-deficient chicken DT40 whole cell extract using 5'-[32P]-labeled single-stranded DNA oligonucleotide containing 3'-p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetTyrosyl-DNA phosphodiesterase 1(Human)
Purdue University

Curated by ChEMBL
LigandPNGBDBM50388546(CHEMBL333363 | CHEMBL213072)
Affinity DataKi:  3.19E+3nMAssay Description:Competitive inhibition of human recombinant Tdp1 after 1 hr by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed