BDBM50388241 CHEMBL1719251

SMILES CC(C)N1CCc2c(C1)sc(NC(C)=O)c2-c1nc2ccccc2o1

InChI Key InChIKey=RGLVQNVGGWMTAJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50388241   

TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50388241(CHEMBL1719251)
Affinity DataIC50: 2.04E+4nMAssay Description:Inhibition of human recombinant APE1 after 15 mins by fluorescence based HTS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50388241(CHEMBL1719251)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of recombinant APE1 using [35P]-5'-AP-DNA as substrate incubated for 15 mins prior to substrate addition measured after 5 mins by PAGE ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed