BDBM50387568 CHEMBL2057713

SMILES C1CC2(CN1c1cccnc1)CC1CCN2CC1

InChI Key InChIKey=RHQJWLPJMQCJOF-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50387568   

LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataEC50:  6.90E+3nMAssay Description:Antagonist activity at human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cells assessed as calcium flux by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataKi:  32nMAssay Description:Displacement of [3H]-epibatidine from human nAChR alpha4beta2 expressed in human SH-EP1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataKi:  1.10E+3nMAssay Description:Binding affinity to human ganglionic nAChR alpha3beta4 expressed in human SHSY-5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387568(CHEMBL2057713)
Affinity DataKi:  8.00E+3nMAssay Description:Binding affinity to human nAChR alpha7 expressed in HEK cells coexpressing RIC3More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed