BDBM50387528 CHEMBL2059908

SMILES CS(=O)(=O)c1cncc(c1)-c1ccc2nc(N)nn2c1

InChI Key InChIKey=NEEIFTJBPMCSFH-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50387528   

LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of fMLP-induced neutrophil migration assay by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kgamma by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kdelta by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha by high throughput chemoproteomics binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PI3Kgamma assessed as inhibition of C5a-induced AKT phosphorylation at Ser473 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 100nMAssay Description:Inhibition of PI3Kgamma in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of PI3Kalpha in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of PI3Kbeta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
LigandPNGBDBM50387528(CHEMBL2059908)
Affinity DataIC50: 6.31E+3nMAssay Description:Inhibition of PI3Kdelta in human HL60 cell lysate by kinobead assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed