BDBM50387409 CHEMBL2047246

SMILES Nc1nc2cc3ccccc3c2c(Nc2cccc(F)c2)[nH]1

InChI Key InChIKey=FHPYQJSDUHOIPA-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50387409   

TargetDihydroorotate dehydrogenase (quinone), mitochondrial(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50387409(CHEMBL2047246)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human DHODHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor beta(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50387409(CHEMBL2047246)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of PDGFRbeta in human SF539 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50387409(CHEMBL2047246)
Affinity DataIC50: 5.57E+4nMAssay Description:Inhibition of VEGFR2 in human U251 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Duquesne University

Curated by ChEMBL
LigandPNGBDBM50387409(CHEMBL2047246)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of EGFR in human A431 cells pretreated for 60 mins measured after 1 hr by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed