BDBM50387290 CHEMBL2048855

SMILES Cc1csc(n1)N(C1CC1)C(=O)CSc1ccc(nn1)-c1ccccc1

InChI Key InChIKey=DPONSKCACOZTGN-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50387290   

TargetSolute carrier family 12 member 5(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50387290(CHEMBL2048855)
Affinity DataIC50: 61nMAssay Description:Antagonist activity at KCC2 expressed in human HEK293 cells assessed as decrease in Tl-stimulated fluorescence increase after 8 mins by fluorescence ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50387290(CHEMBL2048855)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50387290(CHEMBL2048855)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50387290(CHEMBL2048855)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Vanderbilt University School of Medicine

Curated by ChEMBL
LigandPNGBDBM50387290(CHEMBL2048855)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed